‘Groundbreaking’ cure for deadly asbestos-related cancer could be near
By Eric Gaillard, Reuters.com
A Kiwi professor has developed a new treatment that has already saved one man’s life and could possibly help thousands more defeat mesothelioma – an aggressive cancer caused by exposure to asbestos. The disease results in death shortly after diagnosis.
ADRI researchers teamed up with a Sydney-based biotech company, EnGenelC, to use a “futuristic new drug delivery system that relies on nanotechnology and guiding antibodies.” Using animal models, human mesothelioma tumors have been treated with antibody-guided minicells containing microRNA mimics – a combination dubbed TargomiRs.
“We have found an amazing inhibition of tumor growth. The results were far in excess of what have been seen with other experimental therapies in this model, and we are very excited about it,” ADRI senior researcher Dr Reid said.
Putting the microRNA inside nanocells was pretty much like using a Trojan horse, Dr Reid told ABC Australia.
“A nanocell is a delivery vehicle. You can package basically anything in there that you like, so a chemotherapy drug — or in our case a mini-gene — and then it’s injected into the body.” Read more